Book The Best Hotels in Southeast Iowa for 2026 from CA $75 - Fully Refundable Options

A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

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Go beyond your typical stay in Southeast Iowa

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Our top choices for Southeast Iowa hotels

A lobby with a stone fireplace, comfortable seating, and a flat-screen TV mounted on the wall.

A spacious lobby with a leather sofa, dining area, and a TV mounted on a stone wall.

A reception area with a reception desk, a plant, and a sign for Boulders Inn & Suites.

A hotel room with two beds, a television, a desk with a lamp, and a chair.

1. Cobblestone Inn & Suites - Fort Madison

Fort Madison

Hunter

CA $134

CA $150 total

includes taxes & fees

Sep 27 - Sep 28

A spacious living area with a wooden staircase, a stone fireplace, and a reception desk.

A hotel room with two beds, a large window, a standing lamp, and a patterned carpet.

A reception area with a stone wall, wooden reception desk, and a sign that reads "Quality".

An indoor swimming pool with clear water, surrounded by a white fence, and equipped with multiple entry points and seating areas.

2. Quality Inn & Suites Fort Madison near Hwy 61

Fort Madison

Sharon

CA $129

CA $144 total

includes taxes & fees

Sep 27 - Sep 28

A spacious living room with a large sofa, two armchairs, a coffee table, and a fireplace.

A hotel room with a bed, a TV, a desk, and a chair.

An indoor swimming pool with wooden walls and a balcony.

A cozy living room with a grey sofa, two patterned armchairs, a wooden coffee table, and a brick accent wall.

3. AmericInn by Wyndham Mount Pleasant

Mount Pleasant

Terri

CA $119

CA $133 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a bed, a sofa, a small table, a chair, a nightstand, and a painting on the wall.

A home gym with a treadmill, elliptical, and stationary bike, a large mirror, and a framed picture on the wall.

A modern kitchen with a dining area, featuring a central island, built-in appliances, and a large window with blinds.

A modern reception area with a dark granite counter, light-colored walls, and a seating area with a sofa and chairs.

4. Best Western Mt. Pleasant Inn

Mount Pleasant

Paul

CA $110

CA $123 total

includes taxes & fees

Oct 1 - Oct 2

An indoor swimming pool with a wooden ceiling, grey tiled floor, and several lounge chairs and tables around the pool area.

A hotel room with a large bed, a desk with a computer, a chair, a window with curtains, and a view of the city.

A spa area with a hot tub, wooden ceiling, and tiled walls.

A multi-story hotel with a central entrance, a parking lot, and a clear sky.

5. Quality Inn & Suites Keokuk North

Keokuk

Susan

CA $139

CA $156 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a desk, a chair, and a large window.

A bathroom with a bathtub, toilet, and sink.

A reception area with a white sofa, a potted plant, and a framed picture on the wall.

A Super 8 motel with a brick facade, a covered entrance, and a parking lot with cars.

6. Super 8 by Wyndham Mt Pleasant

Mount Pleasant

frank

CA $120

CA $134 total

includes taxes & fees

Sep 27 - Sep 28

A row of single-family homes with a well-maintained lawn and a tree in the foreground.

A modern kitchen with wooden cabinets, a white countertop, and a dining area with a white table and chairs.

A bedroom with a large bed, a bedside table with a lamp, a window with blinds, and a framed picture on the wall.

A compact kitchen with wooden cabinets, a microwave, a coffee maker, and a dishwasher.

7. Nauvoo Vacation Villas & Condos

Nauvoo

Renae

CA $203

CA $215 total

includes taxes & fees

Sep 27 - Sep 28

A large indoor swimming pool with a lifeguard chair, poolside chairs, and a view of the outside through large windows.

A modern hotel room with a large bed, two bedside tables with lamps, a small sofa, and a desk.

A Hampton Inn hotel with a covered entrance, a well-lit facade, and a landscaped front yard.

A breakfast buffet area with a sign reading "EAT HERE" and various food items like cereal and pastries.

8. Hampton Inn Keokuk

Keokuk

Kristopher

CA $164

CA $183 total

includes taxes & fees

Oct 9 - Oct 10

A park bench and a lamppost with flowers in the foreground.

A room with ornate woodwork, a chandelier, and patterned furniture.

A dining table with plates of food, candles, and a lamp.

A two-story brick building with a green porch and a pathway leading to the entrance.

9. Nauvoo Grand Bed & Breakfast

Nauvoo

Henze

CA $231

CA $261 total

includes taxes & fees

Oct 26 - Oct 27

A patio area with Adirondack chairs and a central fire pit.

A snack and sundries section with shelves stocked with various products, a chalkboard with 'Snack!' written on it, and a 'Treats' sign above a display case.

A hotel room with a bed, a desk, a chair, and a TV.

A modern hotel with a brick facade, large windows, and a covered entrance.

10. Hampton Inn & Suites Burlington

Burlington

Susan

CA $173

CA $206 total

includes taxes & fees

Oct 1 - Oct 2

An indoor swimming pool with a wooden ceiling and walls, a bench, and a rack of towels.

A guest registration area with a counter, informational signs, and various items on shelves.

A brick building with a sign for Nauvoo Family Inn & Suites, featuring a traditional design with a tower and arched windows.

A hotel room with a bed, bedside lamps, a nightstand, a refrigerator, and a wooden headboard.

11. The Inn at Old Nauvoo

Nauvoo

Cindy

CA $211

CA $239 total

includes taxes & fees

Sep 28 - Sep 29

A room with a large window, a sofa, and a chair.

A living room with a flat-screen TV on a white console, a grey sofa, and a framed picture on the wall.

A staircase with red carpeted steps leading to a landing with white doors and a red EXIT sign.

A bedroom with two beds, a ceiling fan, a TV, and a dresser.

12. Nauvoo Temple House Hotel

Nauvoo

CA $186

CA $219 total

includes taxes & fees

Oct 5 - Oct 6

A well-lit indoor swimming pool with wooden walls and ceiling, surrounded by lounge chairs and umbrellas.

A hotel with a covered entrance, a parking lot, and a sign indicating it is an Embassy Suites location.

A restaurant with wooden furniture, a TV, a refrigerator, and a coffee machine.

A spacious lobby with a high ceiling, wooden staircase, and a reception desk.

13. AmericInn by Wyndham West Burlington

West Burlington

Jacqueline

CA $78

CA $87 total

includes taxes & fees

Oct 4 - Oct 5

A bedroom with a bed, a wooden headboard, a nightstand, a lamp, a rug, and a door.

A dining area with a round table set for four, a wooden cabinet, and a kitchen area with shelves stocked with kitchenware.

A stone building with a wooden door, illuminated by exterior lighting.

A brick building with a porch, white doors, and hanging lights.

14. Willard Richards Inn

Nauvoo

Dr. Shawn

CA $313

CA $376 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with a bed, a sofa, a chair, and a nightstand with lamps.

A bathroom with a marble-tiled wall, a large bathtub, a wooden vanity with a television, and a patterned rug.

A hotel lobby with red seating, a checkered floor, and a large beverage dispenser.

A lobby with a reception desk, red patterned seating, a round beige ottoman, and a potted plant.

15. Quality Inn & Suites Mount Pleasant

Mount Pleasant

Wesley

CA $101

CA $113 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a large wall-mounted picture, a desk with a lamp, and a window with curtains.

A breakfast area with a counter, seating, and a vending machine.

A hotel corridor with patterned carpet, doors on both sides, and an EXIT sign above the right door.

A staircase leading to a room with a black leather sofa, a framed picture on the wall, and a poster advertising an auction.

16. Super 8 by Wyndham Keokuk

Keokuk

Roger

CA $84

CA $94 total

includes taxes & fees

Oct 1 - Oct 2

A Holiday Inn Express hotel with a covered entrance, multiple windows, and a well-lit facade.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A hotel reception area with a modern design, featuring a reception desk and a wall-mounted information board.

A hotel room with a bed, a desk, a chair, a window, and a bathtub.

17. Holiday Inn Express Hotel & Suites Burlington by IHG

Burlington

Christina

CA $197

CA $226 total

includes taxes & fees

Oct 9 - Oct 10

A lobby with a fireplace, seating area, and an exit sign.

A reception area with a wooden reception desk, a red accent wall, and a kitchenette with shelves stocked with snacks.

A modern kitchen with a microwave, coffee machine, and a juice dispenser. There is a dining area with wooden tables and chairs.

A hotel room with a sofa, ottomans, a chair, a bed, and a desk. There are framed pictures on the wall and a window with curtains.

18. Comfort Suites Burlington

Burlington

Shawn

CA $149

CA $175 total

includes taxes & fees

Oct 25 - Oct 26

A large, two-story house with a porch, surrounded by lush green lawns and trees.

A hallway with a black wall, a white vase with branches, and two white robes hanging on a rack.

A living room with a dark wall, a chandelier, a fireplace, and a large clock.

A black fireplace with a TV above it, a chandelier, and a door leading to another room.

19. Evans Holly Grove Inn B&B

Burlington

Alisa

CA $168

CA $188 total

includes taxes & fees

Oct 9 - Oct 10

A compact kitchen with a microwave, stove, and sink. There is a cabinet with a mirror above the sink and a small shelf above the microwave. The kitchen has a tiled floor and yellow walls.

A reception desk with a wooden panel, a tiled floor, a chair, and a door.

A hotel room with two beds, a desk with a chair, a TV, a desk lamp, a microwave, and a painting on the wall.

A small bathroom with a sink, mirror, and a microwave.

20. Budget Inn

Keokuk

Deanna

CA $89

CA $99 total

includes taxes & fees

Oct 11 - Oct 12

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Stay near popular Southeast Iowa attractions

Joseph Smith Historic Site

9.2/10 (162 reviews)

You can learn about the history of Nauvoo when you stop by Joseph Smith Historic Site. While you're in the area, stroll along the riverfront.

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Historic Nauvoo

9.6/10 (269 reviews)

Find out about the history of Nauvoo when you spend time at Historic Nauvoo. While you're in the area, stroll along the riverfront.

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Snake Alley

8.6/10 (172 reviews)

Learn about the local history of Burlington when you take a trip to Snake Alley. Visit the area's casinos, or simply enjoy its bars.

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Lacey-Keosauqua State Park

8.6/10 (15 reviews)

Commune with nature and explore the great outdoors at Lacey-Keosauqua State Park during your travels in Keosauqua. Wander the parks and lakeside while you're in the area.

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North Lee County Historical Society

7.6/10 (17 reviews)

You can browse the exhibits at North Lee County Historical Society, a museum with a storied past, during your travels to Fort Madison. While you're in the area, stroll along the riverfront.

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Lake Sugema

7.0/10 (2 reviews)

Commune with nature and explore the great outdoors at Lake Sugema during your travels in Keosauqua. Wander the parks and lakeside while you're in the area.

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C.E. Richards Arena

7.4/10 (18 reviews)

You can take time to visit C.E. Richards Arena during your travels to Fort Madison. Wander the riverfront in this family-friendly area.

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Fort Madison Marina

7.6/10 (12 reviews)

Explore the waterfront in Fort Madison with a trip to Fort Madison Marina. Wander the riverfront in this family-friendly area.

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Learn more about Southeast Iowa

Experience the family-friendly area of Southeast Iowa—a scenic riverfront, shopping, and sights from Geode State Park to Devils Island.

See all hotels in Southeast Iowa

Top Southeast Iowa Hotel Reviews

Quality Inn & Suites Keokuk North

8/10 Good

"Clean room, breakfast"

Quality Inn & Suites Mount Pleasant

10/10 Excellent

"Friendly staff. Room was clean. Safe and quiet location"

Best Western Mt. Pleasant Inn

10/10 Excellent

"Everything was great! Clean and comfortable, though just a bit “dated.” Staff was friendly and helpful. Breakfast was wonderful! We would stay again!"

Nauvoo Temple House Hotel

10/10 Excellent

"This hotel is located across the street from the Temple and the commercial district is very walkable. Our room was located in the basement of a very quaint historic building, but it was not clear to us initially that we had to drive to another hotel to pick up the keys. But....we were able to park just outside our room, which was a plus. A/C was great. Breakfast was minimal with no hot food."

AmericInn by Wyndham West Burlington

10/10 Excellent

"Good"

Super 8 by Wyndham Fort Madison

8/10 Good

"The facility and room were wonderful. The only negative was the so called breakfast. There was no protein, only instant oatmeal, packaged pancakes/waffles, yogurt, boiled eggs, milk and juice."

The Inn at Old Nauvoo

8/10 Good

"When I arrived, the staff said my Expedia account had put me in 3 different room for the 3 nights I was staying! Aarg!!!! That was as frustrating! It happened last time I stayed at this hotel and I assumed it was as them. No, EXPEDIA!! Please never do this to me again! Luckily, they noticed it and changed it!"

Nauvoo Vacation Villas & Condos

10/10 Excellent

"Very happy with our unit and the kindness shown by the office staff 😊"

AmericInn by Wyndham Mount Pleasant

10/10 Excellent

"Clean room. Nice breakfast"

More cheap stays in Southeast Iowa

Quality Inn & Suites Fort Madison near Hwy 61

6169 Reve Ct Fort Madison IA

CA $129

CA $144 total

Sep 27 - Sep 28

includes taxes & fees

8.6/10 Excellent! (655 reviews)

Cobblestone Hotel & Suites - Ottumwa

108 Church St Ottumwa IA

CA $133

CA $149 total

Oct 2 - Oct 3

includes taxes & fees

9.4/10 Exceptional! (341 reviews)